ExplodeLayout: Comprehending Patient Subgroups in Large Networks

Enabling Comprehension of Patient Subgroups and Characteristics in Large Bipartite Networks: Implications for Precision Medicine

A primary goal of precision medicine is to identify patient subgroups based on their characteristics (e.g., comorbidities or genes) with the goal of designing more targeted interventions. While network visualization methods such as Fruchterman-Reingold have been used to successfully identify such patient subgroups in small to medium sized data sets, they often fail to reveal comprehensible visu...

Decentralized Interaction Estimators in Large Scale Power Systems with Neural Networks.

LPKP: location-based probabilistic key pre-distribution scheme for large-scale wireless sensor networks using graph coloring

Communication security of wireless sensor networks is achieved using cryptographic keys assigned to the nodes. Due to resource constraints in such networks, random key pre-distribution schemes are of high interest. Although in most of these schemes no location information is considered, there are scenarios that location information can be obtained by nodes after their deployment. In this paper,...

iSubgraph: Integrative Genomics for Subgroup Discovery in Hepatocellular Carcinoma Using Graph Mining and Mixture Models

The high tumor heterogeneity makes it very challenging to identify key tumorigenic pathways as therapeutic targets. The integration of multiple omics data is a promising approach to identify driving regulatory networks in patient subgroups. Here, we propose a novel conceptual framework to discover patterns of miRNA-gene networks, observed frequently up- or down-regulated in a group of patients ...

L2 Learners’ Enhanced Pragmatic Comprehension of Implicatures via Computer-Mediated Communication and Social Media Networks

Second or foreign language (L2) learners’ development of interlanguage pragmatic (ILP) competence to understand and properly interpret utterances under certain social and cultural circumstances plays a pivotal role in the achievement of communicative competence. The current study was designed to explore the effects of synchronous computer-mediated communication (SCMC) and asynchronous com...